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MeditationScience

The Science of Meditation: What Research Actually Shows

A comprehensive, regularly updated guide to what neuroscience has confirmed about meditation's effects on the brain, body, and cognition.

12 min readFebruary 15, 202563 references cited003

Moving Past the Hype

Meditation has been practiced for millennia, but rigorous scientific study of its effects is relatively recent. The field has exploded since the early 2000s — PubMed now lists thousands of studies on meditation. But quantity doesn't equal quality. A critical review by Goyal et al. (2014) in JAMA Internal Medicine screened over 18,000 citations and included only 47 trials — with just 10 rated as good quality. This article focuses on what that rigorous evidence shows.

Effects on Stress and Anxiety

The strongest evidence for meditation is in stress reduction. Goyal's meta-analysis found moderate evidence that mindfulness meditation programs reduce anxiety (effect size 0.38), depression (0.30), and pain (0.33). To put this in context, these effect sizes are comparable to the effects of antidepressant medications. A more recent systematic review by Goldberg et al. (2022) across 44 meta-analyses encompassing 336 RCTs confirmed these findings and showed the effects are maintained at follow-up periods of 3-6 months.

Attention and Cognitive Performance

A systematic review by Lao et al. (2016) examined meditation's effects across three attention subsystems: alerting, orienting, and executive attention. The results showed significant improvements in executive attention (the ability to manage conflicting information) and moderate improvements in alerting (maintaining readiness). These effects were dose-dependent — more practice produced larger improvements.

Emotional Regulation

Meditation appears to change how the brain processes emotions at a fundamental level. Desbordes et al. (2012) used fMRI to show that after 8 weeks of mindfulness training, amygdala reactivity to emotional stimuli was reduced even in non-meditative states. This suggests meditation produces trait changes, not just temporary state changes. The emotional regulation benefits extend to improved interpersonal relationships, reduced rumination, and greater emotional granularity.

What Meditation Doesn't Do

Intellectual honesty requires acknowledging the limits. There is currently insufficient evidence that meditation enhances IQ, prevents dementia, cures clinical depression as a standalone treatment, or produces supernatural experiences. Some meditation practices can produce adverse effects in individuals with trauma histories. Cognic builds on what the evidence supports, and clearly delineates where the evidence ends.

References

  1. [1]Goyal, M., et al. (2014). Meditation programs for psychological stress and well-being. JAMA Internal Medicine, 174(3), 357-368.
  2. [2]Goldberg, S. B., et al. (2022). The empirical status of mindfulness-based interventions: A systematic review of 44 meta-analyses of randomized controlled trials. Perspectives on Psychological Science, 17(1), 108-130.
  3. [3]Lao, S. A., et al. (2016). When using mindfulness? Mindfulness, 7(1), 210-223.
  4. [4]Desbordes, G., et al. (2012). Effects of mindful-attention and compassion meditation on amygdala response. Frontiers in Human Neuroscience, 6, 292.